Robbie Henshaw, Ross Byrne, Dan Sheehan, Tadhg Furlong and Jack Conan have all been included in the Leinster side for Saturday's BKT United Rugby Championship interpro with Munster at the Aviva Stadium.
The Ireland internationals all come into the starting side, with head coach Leo Cullen selecting his strongest available XV for their first Irish derby of the season.
It amounts to five changes from last weekend's win against the Scarlets, with Henshaw and Conan coming in for their first appearances of the season.
Henshaw replaces Jamie Osborne in the centre where he partners co-captain Garry Ringrose, while Ross Byrne steps in at out-half having appeared off the bench last week.
Jamison Gibson-Park continues at scrum-half, while the back-three is unchanged, with Hugo Keenan at full-back, with Jordan Larmour and Jimmy O'Brien on the wings.
Up front, Dan Sheehan swaps with Rónan Kelleher at hooker, while Tadhg Furlong also steps into the starting side, joining Andrew Porter at prop. Joe McCarthy and James Ryan pack down behind them in the second row.
Conan makes his first Leinster appearance of the season, coming in at blindside flanker, while Caelan Doris and Josh van der Flier complete the side.
Munster have made six changes from last weekend's win over the Stormers, with hooker Diarmuid Barron (above) captaining the side.
Peter O'Mahony, who this week confirmed he would be stepping down as skipper, misses out due to injury, as does fellow back-row Jack O'Donoghue.
Head coach Rowntree has made a number of interesting calls, with Tom Ahern drafted into the first team at blind side flanker, in a first back row appearance for the Waterford man, who usually features at lock.
He joins Gavin Coombes and John Hodnett at the back of the scrum, with Jean Kleyn returning at second row to partner Tadhg Beirne.
In the front row Stephen Archer starts, with the tighthead set to make a record 269th appearance for the province, passing Donncha O'Callaghan's longtime record.
Craig Casey and Jack Crowley continue in the half-backs, while Rory Scannell replaces Alex Nankivell in the centre where he is joined by Antoine Frisch.
Shane Daly shifts out to the wing to accommodate Simon Zebo, who makes his first appearance of the season, while Calvin Nash continues on the right wing.
Leinster: Hugo Keenan; Jordan Larmour, Garry Ringrose (co-capt), Robbie Henshaw, Jimmy O'Brien; Ross Byrne, Jamison Gibson-Park; Andrew Porter, Dan Sheehan, Tadhg Furlong; Joe McCarthy, James Ryan (co-capt); Jack Conan, Josh van der Flier, Caelan Doris.
Replacements: Rónan Kelleher, Jack Boyle, Michael Ala'alatoa, Ross Molony, James Culhane, Ben Murphy, Ciarán Frawley, Scott Penny
Munster: Simon Zebo; Calvin Nash, Antoine Frisch, Rory Scannell, Shane Daly; Jack Crowley, Craig Casey; Jeremy Loughman, Diarmuid Barron (capt), Stephen Archer; Jean Kleyn, Tadhg Beirne; Tom Ahern, John Hodnett, Gavin Coombes.
Replacements: Scott Buckley, Dave Kilcoyne, John Ryan, Brian Gleeson, Alex Kendellen, Conor Murray, Tony Butler, Shay McCarthy.
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Watch live coverage of the Vodacom Bulls v Connacht in the BKT United Rugby Championship on Saturday from 2.30pm on RTÉ2 and RTÉ Player, and listen to live commentary on RTÉ Radio 1
Follow a live blog of Leinster v Munster on Saturday from 6.30pm on on www.rte.ie/sport and the RTÉ News app and listen to live commentary on RTÉ Radio 1
